User blog comment:DeadpoolN7/Mass Effect 4/@comment-4452849-20121016140117

Well on that website that talked about Omega, there was some talk about the Illusive Man's origins and maybe the First Contact War as well. As for sequels, while some imaginings are popping in my head, it might take time for it to continue. And I guess it would depend on where it's last saved at, although I think the refusal and low destroy endings should be like the all dead ending, non-canon.