User blog comment:Tiredman2/What is your favorite moment in the Mass Effect trilogy?/@comment-1679409-20120824045607

Off the top of my head, I have three in the running:

1) The Reaper fleet at the end of ME2.

2) The leaving Earth cutscene (the first time I've ever almost cried while playing a video game)

3) The cutscenes leading up to Priority: Earth, especially the part when the fleets are arriving.

Speaking of that last one, the music during that cutscene was awesome, but someone made it even more awesome by setting it to the "Suicide Mission" theme from ME2. See here: http://youtu.be/-7_BCTtCrxQ