User blog comment:James12708/Reapers VS. Forerunners VS. Angels from Darksiders VS. Humanity from Halo VS. Council and humanity from Mass Effect VS. Imperium of Man/@comment-50.80.96.33-20130112163411/@comment-4950455-20130123004849

The Reapers do seem to have some kind of ability to resist energy weapons - in Javik's memories during Priority: Eden Prime they're seen shrugging off Prothean particle beams.