User blog comment:N7EagleEye/New Mass Effect 4 Details/@comment-11305011-20130604013423

UPDATE FOR ANYONE WHO CARES OR DOESN'T KNOW THE FOLLOWING:
--Executive Producer Casey Hudson This quote shows that the possibility of a Mass Effect 4 spinoff isn't out of the question.src
 * It has been confirmed that the next installment in the Mass Effect series will be powered by the Frostbite 3 engine.src
 * "There's so much that could be told in the Mass Effect universe,' Hudson said. 'It'd be cool to do something completely unrelated to the larger storyline, like a story about a private investigator on the Citadel. Or maybe something detailing Garrus' time in C-Sec."
 * On the Bioware Social Network forum, the community coordinator disclosed that the next installment in the series is being developed by a new team at the Montreal studio with additional help from the Edmonton branch.src