User blog comment:James12708/Possibility of a Mass Effect 4/@comment-5173770-20120715210832

Bioware could keep pumping out the DLCs till the cows come home. There's a thousand--if not more--variables that Bioware can explore. The games were designed to cover Commander Shepard's story, but as Miranda once said, "he's just one man." There's an infinite amount of scenarios Bioware can engage without making another game.

... but that doesn't mean I wouldn't be super-excited if they DID decide to produce a fourth game. I love this series!