User blog comment:Vanguard13/Pick Your Poison (Ammo, that is)/@comment-5287758-20120809210501

ME1: Proton rounds 'cos they can bypass shields and cause some damage to armor/health.

ME2: Shredder rounds, 'cos they are very very effective against any organic opponents which are most numerous in the game.

ME3: Nothing's beating the incendiary ammo! I love seeing the Reapers and Cerberus when they are on fire, dancing abt on the battlefield, easy for me to take 'em out.