User blog comment:Suparockr/List of Plotholes throughout the series/@comment-24163193-20141103163437

WHy are the reapers and the Catalyst NOT more interested in other galaxies? If this many different races and intelligences can arise in this one galaxy, isn't it plausible to think that something even more powerful has arisen in other galaxies that could very well threaten life here, you know the one reason the intelligence exists, it's first prerogative? Especially since said distant races or intelligences haven't been harvested every 50k years and thusly can have surpassed everything ever existed here in this galaxy? Because they've had enough time.

It exists to preserve life, but ignores the biggest threat to life according to itself. Not so much "plot" hole as "Fundament of the entire franchise dissovant" really...