User blog comment:Legionwrex/Why Destroy is the worst ending (besides refusal)./@comment-4237253-20120707170543/@comment-899316-20120707204036

Under the Catalyst, yes. Under Shepard, probably not. Shepbinger would likely wipe out the attacking synthetics, rather than the organics that are under attack. This is implied by Paragon Shepard's Control dialog. He/she says that they will act as the guardian of galactic society. That seems a far sight different from harvesting it.