User blog comment:TheUnseelieCourt/Next Mass Effect To Be Developed By Bioware Montreal/@comment-2250460-20121112203419/@comment-1991014-20121113013021

Then the only real possibility is a prequel. A side story game would be so uninteresting and really, that should be saved for DLC. If you're going to do a whole new game, there's got to be something more than 'small' like going after a merc or rogue agent, as I've heard some people suggest. This is a space opera game and that would make a very uninteresting plot in a galaxy spanning sci-fi. Therefore, it's either gonna be a prequel with some major plotline (and what would this be, First Contact War?) or a new threat equal or greater than the Reapers will be introduced.