User blog comment:Nord Ronnoc/Mass Effect San Diego Comic Con - What We Know So Far/@comment-9753034-20140731124449

Personally I'm a little excited about the confirmation that the protagonist has "something to do with N7" (granted, we did see N7 armor as far back as last N7 day) as well as the return of a ground vehicle. I have seen nothing yet that "strongly implies" anything will be set in another galaxy, however; it would fundamentally change the parameters of the existing series, and it should be kept in mind that there are plenty of new and uncharted areas in the Milky Way since many races and (literally) tons of systems exist but haven't been featured yet.

Out of the fruits of the panel I'd recommend these, both of which have been retweeted by BioWare peeps:
 * Nerd Appropriate's full coverage
 * Andrea Rene's Escapist News report ("conceptual prototype" video footage of the new Mako)