User blog comment:Arbington/ME3 Theories/@comment-1691295-20100628075425

I suspect quite a few characters from ME2 won't return as squadmates, for various reasons.

Wrex, I don't think will return, but I do think, if he survived, that he will be a major supporting character, leading the united krogan against the Reapers. Same goes for Liara. She never was a soldier or a fighter, and it didn't really make much sense outside of gameplay reasons for her to be a squadmate in ME1, let alone ME2 or 3.

Thane might be out, due to his illness, I don't see BioWare doing a sudden 'he's cured'. It would come across way to much as pandering to fans, and would be incredibly lame. As good as the character is, magically curing him of an ailment that was the driving force behind his character is just bad storytelling. I do see him sticking around though as a supporting character, and there's a lot of potential for a really dramatic and unique conclusion to his romance, if the player is doing it, I just don't think that requires him to be a squadmate.

Legion, if he survived, I can see going back to the geth and will act as a supporting character, much like Wrex and the krogan.

I don't see any reason a loyal Grunt wouldn't stick around, nor Jacob and Miranda.

Jack is more up in the air, and I can see her situation developing quite differently based on how she's treated.

Samara I have no idea, and frankly don't care.

Mordin is an interesting case, since apparently he's the most common death in the finale, so maybe he'll just be a supporting character.

On the other hand, they could all just not be squadmates and there'll be new characters.

There are so many ways BioWare could approach this, I'll be fascinated to see how it plays out.