User blog comment:JakePT/ME3 Info Blitz Begins in April/@comment-1853169-20110330170312/@comment-1691295-20110331031941

I wouldn't necessarily mind multiplayer. So long as it doesn't detract from the rest of the game. If they can do everything they want in ME3 single-player and have multiplayer, then I don't really mind.

The third game seems the logical place to put it if that's what they want to do though.