User blog comment:Lancer1289/BioWare gets on the Multiplayer bandwagon/@comment-2127131-20111011080748/@comment-1655340-20111011081344

Due to the nature of the game, and the storyline, there is a loose connection between the two. But, like I said in my WoT reply below, and as was mentioned in the MP-revealing post, Neither Shepard nor any of the squad members appear at all in MP. So, all we're affecting really is the outcome of random battles across the galaxy that Shepard isn't involved in.