User blog comment:Legionwrex/Why Destroy is the worst ending (besides refusal)./@comment-5236409-20120709155811/@comment-899316-20120709162028

You may wish to note that synthetic life does not only refer to Reapers. Indeed, nobody has thus far implied that, after Destroy, new Reapers would be made. People, myself included, have merely pointed out that eventually new synthetic beings, more akin to the geth or the zha'til than to the Reapers, will be created. Then, life will be exterminated in the resulting war.

As for the speculated attack on the Reapers post-Control, I find that to be highly unlikely. As Admiral Hackett quite clearly stated, even with the largest fleet ever assembled at their disposal, the united galaxy could never hope to defeat the Reapers in conventional warfare. To attack them with a weakened fleet would be suicide. Also, seeing as this is all speculatory, why would the Shep-controlled Reapers have to fight back? Couldn't they just leave?