User blog comment:RayShepp654/How to defeat the Reapers Theories/@comment-2130363-20101025161944

Well in Mass Effect 2, we did see how useful the Thanix Cannon was against the Collector ship. How many shots did it take? Two. As Shepard, the first thing I would do is gather as many allies as I can and outfit as many of their ships with the Thanix Cannon as possible. That would most definitely improve their odds of surviving.

I would still like it if they introduced a piece of Prothean technology that we haven't seen yet. Perhaps they found it in another facility similar to Ilos that housed a few dozen Protheans when the Reapers left. It's abandoned of course but they find instead of what happened at Ilos, the Protheans survived and stayed secluded in a system far from any mass relay. Shepard's mission then is to unite the galaxy and most of all, to find the long lost Protehans.