User blog comment:James12708/Reapers VS. Forerunners VS. Angels from Darksiders VS. Humanity from Halo VS. Council and humanity from Mass Effect VS. Imperium of Man/@comment-50.80.96.33-20130122221432/@comment-1786741-20130122225907

While no organic is immune to indoctrination, the Reapers can't magically indoctrinate people like that. Hell, in the entirety of the Mass Effect series indoctrination didn't even compose the bulk of their tactics. All they did was manage to indoctrinate a few influential people (Saren, the Batarians, and Hanar ambassador being the majority of their efforts), the rest of their tactics were being BIG F***ING SHIPS THAT DESTROYED THINGS WITH ZOMBIE GROUND TROOPS. Since the Forerunners can pretty much annihilate that, the Reapers have a snowball's chance in hell of surviving long enough to even indoctrinate a single person.