User blog comment:VicGeorge2K9/Mass Effect 2 PC controls mapped to a gamepad/@comment-1323688-20110526161936

First, you download GlovePIE, install it, and run it. Then, you just copy the above script and paste into the GlovePIE script window and save it as "MassEffect2.PIE". Next, you run the script by clicking on the Run button. You should know that the script is functioning if you're able to move the mouse pointer with the Right Stick. Finally, just run Mass Effect 2 and you're all set.