User blog comment:Agentsmit58/Shepard's story has truly ended and wont have DLC to continue the story!!!/@comment-5159807-20120602183223/@comment-1221773-20120602195208

Probably not. I think two scenarios are likely:

First, indoctrination tech ceases to function after the Reapers are destroyed/controlled. This means Reaper technology can be studied safely.

Second, indoctrination tech continues to function independently of the Reapers, but the galaxy's races are now smart/careful enough to study it and apply it to their own tech without becoming victims. One of the Intel Terminal items explains that remotely-controlled drones can be used to extract tech from Reapers.