User blog comment:JediSpectre117/Regarding the surviving Prothean./@comment-1504310-20120219185955/@comment-118213-20120220155502

I think Ironreaper is right, I seem to remember EDI saying that the Collectors were no longer Prothion one can guess the genetic alterations didn't happen over one generation. "these are no longer Prothions Shepard, their genes show distinct signs of extensive genetic rewrite."