User blog comment:Nord Ronnoc/Details of new Mass Effect game from private PAX presentation/@comment-4950455-20131126011354/@comment-209.145.77.32-20131128185153

If it's a sequel they can't. Quarians can be wiped out in ME3 and the outlook for the Krogan race doesn't look good if the Genophage isn't cured and Wrex is dead.