User blog comment:Arbington/If You Hate Vido Santiago, You'll Love This!/@comment-118213-20120325201549/@comment-118213-20120325215423

That's the point I was making...., for the duration of the game she was staying out of sight of both the Alliance and Cerberus whilst she was busy searching for her sister... the idea is that rather than her searching externally and you talking to her every now and then, she'd be on the Normandy doing that, since it can coincide with Shepard's aims relating to Cerberus.

Very little would actually need changing:

In the Sanctuary mission for example; Miranda can accompany Shepard, and when Shepard looks at the terminals throughout Shepard can both - see Kai Lang (instead of Miranda), and allow Miranda to broadcast her warning to refugees.

Since it's unspecified what exactly Miranda is doing to search for her sister, it wouldn't take much explaining having her on the Normandy - especially due to the resources that would be available to her, including the Shadow Broker.

Though as I said, I don't ever expect this to happen.