User blog comment:The Milkman/The Next Effect/@comment-24174486-20121121115332/@comment-5287758-20121121172849

The endings vary widely sure, there will always be a way to integrate all of them without retconning or making something canon. We can't see the way now, but that doesn't mean its impossible. Bioware has got a lot of time on their hands, they will figure it out, provided they are making a sequel.