M-920 Cain

The M-920 Cain is a heavy weapon from Mass Effect 2.

In-Game Description
The effectiveness and efficiency of mass-effect-based weapon technology has rendered large-scale deployment of highly explosive weaponry all but obsolete in infantry weapons. Normandy's scientists have prototyped a modified version of traditional high-explosive rounds that is applied to a 25-gram slug. When accelerated to 5 km/s, the round is devastating. Though a technically inaccurate label, this prototype weapon is nicknamed the "Nuke Launcher," and its high-explosive matrix generates an archetypical mushroom cloud on impact. It inflicts high damage with large area of effect. Very effective against armor, shields, and barriers.

Acquisition
Unlocked at the Normandy research station after three Heavy Weapon Ammo upgrades have been researched. Costs 25,000 iridium.

Player Notes

 * General Notes
 * Video firing the M-920 Cain
 * Very useful against bosses on Insanity.
 * There is an infinity ammo glitch with Cain. Just reload it right after shot and ammo will back to its previous amount. (Unconfirmed)
 * On normal difficulty, the Cain is capable of killing enemies within an extremely large area in a single shot. The Thresher Maw on Tuchanka and the Human-Reaper are the only enemies in the game that the Cain cannot kill instantly; instead, the Cain takes off a little more than half of each boss's life bar. On hardcore and insanity, the Cain is extremely useful for shortening difficult fights, such as Praetorians.
 * Gathering all the heavy weapon ammo you can find will generally allow it to be used once every other mission. However, Cain can only be fired when its ammo count is at 100% or above, meaning that it can only hold enough ammunition to be fired twice (full ammo upgrades bring its capacity to 200%, or 2 shots). If the Cain is shot quickly after the first shot, the charge time would be neglected.
 * It is a devastating weapon. Because of its large damage effect, don't fire it within a small room. A second problem with this weapon is the long 'charging time' before the weapon fires, which forces the player either to expose him/herself to enemy fire, or to hide behind a wall and carefully time the shot in order not to have the slug explode right in front of them.
 * Class Specific Notes
 * For infiltrators, utilising Tactical Cloak is an excellent strategy for negating the M-920's charge up time without being under enemy fire. This is most useful on higher difficulties or against strong enemy types.

Trivia

 * The M-920 Cain is the only heavy weapon available for research that does not unlock a codex entry.