Upgrade Guide

This upgrade guide lists the locations and prices for all equipment and power upgrades available in Mass Effect 2. Upgrades are listed both by their in-game location and by the affected piece of equipment or biotic/tech power.

Note that research costs depend on the number of upgrades researched so far. So the cost for the first first Heavy Pistol Damage upgrade will always be 2,500 Palladium, no matter where acquired, followed by 5,000 and 7,500 for the next two tiers. Acquiring an upgrade from a store does not change the cost of the research upgrades.

Total resources needed to research/buy all useful projects:
 * 195,000 palladium
 * 225,000 platinum (+50,000 for Med-bay Upgrade)
 * 220,000 iridium
 * 31,000 element zero (+5,000 for each Advanced Training and +2,500 for each Retrain Powers)
 * 1,250,000 credits (this includes discounts)

The amount of credits available from a normal play-through covering all missions, assignments and current DLC is 1,061,625 (with a theoretical maximum of 1,105,625 if avoiding the use of medi-gel and heavy weapons and making Renegade choices because of money), so acquiring all upgrades requires importing a level 60 character with the "Rich" achievement from Mass Effect (+150,000) or starting with the "Long Service Medal" achievement bonus (+200,000).

Assignments

 * N7: Anomalous Weather Detected: Damage Protection – Reward
 * N7: MSV Strontium Mule: Heavy Skin Weave – Located at the end of the mission on a hackable terminal with the payload
 * N7: Blood Pack Base: Heavy Weapon Ammo – Reward
 * Project Firewalker: Prothean Site: Biotic Damage - Located at the end of the mission on a research terminal

Citadel

 * Damage Protection – Sold at Saronis Applications
 * Tech Damage – Sold at Saronis Applications
 * Submachine Gun Damage – Sold at Rodam Expeditions
 * Heavy Pistol Damage – Sold at Rodam Expeditions
 * Sniper Rifle Damage – Sold at Rodam Expeditions
 * Medi-Gel Capacity – Sold at Sirta Foundation

Derelict Reaper

 * Sniper Rifle Damage – At the end of a long catwalk where Legion snipes some husks
 * Heavy Skin Weave – In a computer after fighting your first Scion of the level
 * Shotgun Damage – In the middle of a bunch of Scion and husk fights

Disabled Collector Cruiser

 * Damage Protection – On a research terminal before encountering any Collectors
 * Tech Damage – After fighting the Praetorian

Freedom's Progress

 * Heavy Weapon Ammo – On the dead YMIR mech just outside Veetor's shack

Haestrom – Dossier: Tali

 * Heavy Pistol Damage – At the bottom of a stairwell next to the body of a quarian marine at the site of the first fight with the geth (easily missed)
 * Assault Rifle Damage – In the room blocked by the collapsed pillar

Horizon

 * Heavy Skin Weave – On a dead Collector, just after first seeing husks, before examining dead Husk. If you examined husk, you are too late and won't be able to go back.
 * Biotic Damage – On a dead Collector when you first meet a Scion, after finding Delan (easily missed)
 * Retrain Powers - Automatically acquired after completing this area.

Illium

 * Assault Rifle Damage – Sold at Gateway Personal Defense
 * Heavy Skin Weave – Sold at Gateway Personal Defense
 * Submachine Gun Damage – Sold at Gateway Personal Defense
 * Biotic Damage – Sold at Serrice Technology
 * Medi-Gel Capacity – Sold at Serrice Technology
 * Bypass Module – Sold at Serrice Technology
 * Damage Protection – Sold at Gateway Personal Defense. Only available after completing the Collector Ship mission.
 * Tech Damage – Sold at Serrice Technology. Only available after completing the Collector Ship mission.

Illium – Dossier: The Assassin

 * Submachine Gun Damage – Just before the windy bridge

Illium – Dossier: The Justicar

 * Biotic Damage – In the small room with Elnora, the asari hiding behind the desk

Korlus – Dossier: The Warlord

 * Sniper Rifle Damage – At the top of the stair case after the waves of krogans
 * Krogan Vitality – In the same room you find Warlord Okeer

Loyalty Missions

 * Garrus: Eye for an Eye: Sniper Rifle Damage – In a hackable terminal after the room where Fake ID is obtained
 * Grunt: Rite of Passage: Shotgun Damage – Awarded by the shaman automatically
 * Jack: Subject Zero: Biotic Damage – On a hackable computer right before fighting Kureck
 * Jacob: The Gift of Greatness: Heavy Pistol Damage – Just after the barricade is destroyed with the rigged mech
 * Legion: A House Divided: Geth Shield Strength – On a geth terminal found in a room that triggers conversation about the size of the station.
 * Miranda: The Prodigal: Submachine Gun Damage – Found in a shipping container after riding the first elevator
 * Miranda: The Prodigal: Medi-Gel Capacity – On a dead merc after the first elevator ride and sub-machine gun upgrade (easily missed)
 * Mordin: Old Blood: Krogan Vitality – In the same room as the dead female krogan
 * Mordin: Old Blood: Heavy Weapon Ammo – On a hackable research terminal right before Maelon's room
 * Samara: The Ardat-Yakshi: Assault Rifle Damage – On the wall in Morinth's apartment
 * Tali: Treason: Geth Shield Strength – On a Hackable Monitor just after the first room
 * Tali: Treason: Tech Damage – Awarded after trial if Tali is found innocent (either through Charm/Intimidate, Rallying the Crowd, or by handing over evidence (and losing Tali's loyalty permanently)).
 * Thane: Sins of the Father: Heavy Pistol Damage – Immediately at the beginning on the 800 Wards on a datapad
 * Zaeed: The Price of Revenge: Heavy Weapon Ammo/Assault Rifle Damage – On the Paragon path (save the workers) you can find a Heavy Weapons Ammo upgrade, whereas on the Renegade path, you can find an Assault Rifles damage bonus.

Normandy SR2

 * Medi-Gel Capacity – Complete Dr Chakwas' assignment.

Omega

 * Heavy Skin Weave – Sold at Kenn's Salvage
 * Heavy Weapon Ammo – Sold at Kenn's Salvage
 * Shotgun Damage – Sold at Kenn's Salvage
 * Sniper Rifle Damage – Sold at Omega Market
 * Hack Module – Sold at Harrot's Emporium

Omega – Dossier: The Professor

 * Assault Rifle Damage – In the quarantine area, just after a barricade of mercs, Examine a "Modified Assault Rifle" near a Blue Sun Corpse.
 * Medi-Gel Capacity – In the room opposite to the one Mordin is in inside the Clinic.

Omega – Dossier: Archangel

 * Submachine Gun Damage – Right before the assault on Archangel. There is a door you have to bypass close to the gunship (easily missed)
 * Tech Damage – On the ground floor of Archangel's house during the assault, on a shelf near the base of the stairs.

Purgatory – Dossier: The Convict

 * Damage Protection – On a destroyed YMIR mech right after freeing Jack
 * Shotgun Damage – On a dead guard right after destroying the first large mech

Tuchanka

 * Assault Rifle Damage – Sold at Fortack's Database
 * Biotic Damage – Sold at Fortack's Database
 * Heavy Pistol Damage – Sold at Fortack's Database
 * Shotgun Damage – Sold at Fortack's Database
 * Heavy Weapon Ammo – Sold at Ratch's

Upgrades by Type
Prices shown are before the paragon/renegade discount and before the engineer research discount.

Ship Upgrades
Note: Upgrades tied to squad mates are also unlocked after gaining their loyalty.

Credits by Location/Mission
This is a list of how many credits are attainable and what missions they are on. Credits that are optional are listed separately from the totals. Power cells and med kits are listed because you can get 100 credits from each of them if you are full, but they are not included in the totals.

These numbers show that if you maximize your credits and purchase no fuel (running on minerals instead), you will still fall 5,575 credits short of purchasing all upgrades; not including trinkets. That's also not taking into account the several thousand you will probably need to spend on probes. So starting bonuses from prior playthroughs are necessary to get all upgrades.