User blog comment:DeadpoolN7/Mass Effect 4/@comment-3430127-20121016130500/@comment-1153722-20121018082207

I don't know, to me, this doesn't exactly look like a preserved Collector base rather than a destroyed one. In my personal experience, when given a choice between good or bad in games, good is always the canon option. Look at inFamous or Star Wars: The Force Unleashed. I'm not saying this has to be the same for Mass Effect, but in my interpretation I will see paragon choices as canon (save for the ME3 ending), and I find this to be the more logical one too.

Of course, if Bioware decides to indeed make "Mass Effect 4" and have it set after the events of Mass Effect 3, they can just pick one of the endings and say that is canon, as they are already doing similar things. It's not a good option, but one I am personally willing to be okay with, as I'm always in favor of a properly laid out canon.