User blog comment:Dragonzzilla/Is It Possible to be a Renegade but Still be Good at the Same Time?/@comment-3399608-20110727091044

It is possible to be Paragon and slightly Renegade or vice versa, but you can't really max out both. If you do choose to do so, you will probably not be able to access some charm/intimidate options (I'm assuming you're not modding).