User blog comment:N7EagleEye/New Mass Effect 4 Details/@comment-4118072-20121019213528

I said this over at another blog but I'll say it again. I'd find it weird playing a mass effect game without any reference to the Reapers. Before ME3 I was perfectly fine with the idea of a RTS or FPS or Star wars battle front type game or an MEgame without Shepard, but now I just don't know, I think I'd find it weird. If before ME3 then you know what lays out there while your playing the character on screen.

If it was taking place during the first contact war, I could help but think as I play as a human or turian that at that moment the Reapers are likely on the move and Sovereign is putting his plans in place