User blog comment:Tiredman2/What is your favorite moment in the Mass Effect trilogy?/@comment-24174486-20120824140051

The moment from Anderson and Udina's opening conversation to the final credits.

... it's hard for me to pick favourite moments, really. But a lot of them come from ME3 due to being the end result of all of the choices I've made throughout the series: curing the genophage, the rachni queen rescue, bringing peace between the geth and quarians, Conrad freaking Verner, and definitely not least putting an end to the Reaper cycles once and for all.