I hang about this particularly thought for a while now.
The Milky Way was/is filled with Reaper Mass Relays, simply to move quickly from A to B and initially to speed up the harvest.
But... there are no Reapers in Andromeda, nor are there Mass Relays. So acutally the whole exploreable space is 1 Starcluster, for FTL drive is the limit.
Except..... the new adversary/dominant race in Andromeda had the same Technological idea to build Mass Effect based transportation devices.
I am really curious on how BW will introduce this problem and implement a viable soultion, because we can't build relays, we simply used them.