These are all ideas I’ve seen floating around whenever there’s discourse around everyone’s most hated assassin so have at it and be sure to let me know the reason behind your choice.

For the Virmire casualty. I picture it as using them as a test bed for Project Lazarus. As a result, they’re deformed, but still identifiable. Cerberus implemented the control chip in their brain that they didn’t use with Shepard.