Well think about it this way back in the 18 century, people didn't even got over 50 years, in the 19 century they nearly got 80 and now 20 century people can get 90 to over 100 years old. What do you think will happen another century? So it could be realistic if you take it from my standpoint.
No protheans are unknown for how long they live could be immortal or reproduce like asari but it’s unknown only prothean we know is Javik and didn’t learn much about that stuff from him