I got curious so i did some research and found this:
2151 - A shipping accident at Singapore International Spaceport exposes downwind communities to containers of dust-form element zero. [Kaidan exposed in utero to element zero] Alliance begins construction of Arcturus Station.
2152 - Roughly 30% of the children born in Singapore after element zero exposure suffer from cancerous growths. 70% seem normal.
2154 - Shepard is born; apparently was exposed in utero to element zero.
2156 - Some children of Singapore exhibit minor telekinetic abilities.
2158 - Humans learn potential of biotics. Original exposures now actively tracked. Roughly 10% of the initial exposed children show some level of biotic ability. Kaidan and Shepard not detected.
2160 - Conatix Ind. contracted to develop biotics program. BAaT training established on Jump Zero.
2163 - Earliest human-compatible biotic implants attempted. L1 implants yield minimal results due to late implantation. Accidental exposures too infrequent to contribute to research in a meaningful way. Second generation exposures "arranged" in a number of drive system failures over populated areas.
2166 - Turian "expert" brought in to Jump Zero to oversee biotic program.
2167 - L2 implants created. Kaidan among first to get the new implants. His potential increases dramatically but with discomfort. Others yield "unfortunate" results.
2168 - Shepard, 14 years old, received secondary exposure to element zero. Permanent biotic inclination manifests.
2169 - Kaidan, 17 years old, accidentally kills trainer after being provoked. Diplomatic incident forces closure of BAaT training. Kaidan refuses further training.
2170 - Biotic training assumed by military and select private R&D companies, renamed divisions of original Conatix Industries. L3 implants created.
2171 - Shepard officially detected as a biotic and fitted with L3 implants at 17.
2173 - Kaidan returns to military on his own terms. One of the few original biotics from the BAaT program that remains "stable." Refuses retrofit.
Apparently this is from the writer that wrote the Codex, it seems secondary exposure is one that happens after someone was exposed to it during pregnancy.