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Mass Effect Wiki
Disambiguous.png This article is about the heavy weapon in Mass Effect 2. For the augmentation in Mass Effect: Andromeda, see Grenade Launcher (augmentation).

The M-100 Grenade Launcher is a heavy weapon in Mass Effect 2.


Rapid-fire grenade launcher favored by Blood Pack vorcha mercenaries. Capable of taking down multiple enemies with a single well-placed shot. Effective against armor, shields, and biotic barriers.


Miranda instructs you to pick up this weapon just before the lift during Prologue: Awakening.

Player Notes

  • This is the first heavy weapon acquired (during the escape from Lazarus Station), and it remains useful throughout the game, possessing good damage, accuracy, capacity, rate of fire, and "crowd control."
  • The Grenade Launcher has a noticeably faster rate of fire when the trigger is repeatedly pressed as opposed to held down.
  • The grenades the M-100 fires follow a straight line trajectory down the crosshair and do not arc with gravity making them fairly easy to aim.
    • The grenades do not seek targets like the ML-77's rockets but the hitbox of the projectile is quite large making targeting fairly forgiving.
    • Aim assistance in Mass Effect 2, even at the lowest settings, can alter the trajectory of grenades when fired, causing them to fire off-center from the crosshair.
  • The M-100 Grenade Launcher deals splash damage, making it a good choice against groups of small targets.
  • M-100 grenades have a significant force component to their detonations. The explosion force will knock most light enemies down and instantly destroy husks.
    • Somewhat uniquely, this force component can work through protection layers (barriers, shields, and armor) provided that the damage of the grenade was sufficient to totally eliminate said protection. Thus, even on Hardcore or Insanity difficulty where husks possess armor, a single grenade from the M-100 can still instantly kill them, and even a shielded enemy can be knocked down if the grenade damage was enough to kill the shield.
    • Grenades that don't immediately destroy the protection layers of a target will still stagger the target briefly in most cases.
  • The M-100 deals damage to Shepard and allies so caution should be used at close ranges.


  • It appears the M-100 had a Codex entry, however it was cut from the final game.
  • A turian soldier in Mass Effect 3 can be seen firing what appears to be a M-100 at a Reaper Destroyer in a cutscene in Priority: Earth. The M-100 is not available for use as an in-game weapon, however.
  • Although the weapon's description makes mention that the Blood Pack's vorcha troops utilize the M-100 as a favored weapon, no Blood Pack troops encountered by Commander Shepard's team are seen wielding the weapon.

See Also