Prisoners are enemies encountered on the Purgatory just after freeing Subject Zero in the mission Dossier: The Convict. They will engage both Blue Suns mercenaries and Shepard.
Prisoners have no armor, shields, or barriers on lower difficulties. On Insanity difficulty, Prisoners' defenses are bolstered with shields.
- Since, for the most part, prisoners only have health, they are ideal targets for pistols, biotic powers, and health-affecting tech powers, such as Mordin's Cryo Blast.